SERVICES

◇ Newly Added Projects on Tumor ◇

 

Test Items

Specimen

Requirements   

Methods

Clinical   Significance

Lung Cancer 10 Genes                

Paraffin-embedded   tissue                

/Fresh tissue                

Next-Generation Sequencing                

To guide targeted drug delivery for lung   cancer.                

Peripheral   blood                

Tumor 534 Genes 

(Including TMB and MSI)                

Paraffin-embedded   tissue                

/Fresh tissue                

To guide the making of individualized therapeutic plan for tumors.                

Peripheral   blood                

Breast Cancer BRCA1/2 Panel                

Saliva                

Auxiliary diagnosis on hereditary breast   and ovarian cancers and screening for high-risk groups.                

Small Package on Colorectum Detection                

KRAS+NRAS+BRAF Mutation                

Paraffin-embedded   tissue                

/Fresh tissue                

ARMS                

To guide the   use of cetuximab and panitumumab.                

Peripheral   blood                

    Small Package on GIST Detection                

C-KIT、PDGFRA Mutation                

Paraffin-embedded   tissue                

/Fresh tissue                

To guide the use of imatinib /sunitinib.                

Peripheral   blood                

Septin9 Gene Methylation                

Peripheral   blood                

Methylation PCR                

The screening for colorectal cancer.                

Expression Level of PCA3                

Urine                

RT-PCR                

Early auxiliary diagnosis on prostate cancer.                 

 

◇ Tumor Detection Package ◇

 

Cancer Classification

Test Items

Specimen

Requirements

Breast Cancer

Breast Cancer Prognosis+ Risk of Recurrence+   ParpiInhibitor Package (Her2 Negative or TNB)

Breast cancer gene 21+BRAC1/2

Tissue   

Breast Cancer Prognosis+ Risk of   Recurrence+ Herceptin Package (Her2-Positive Patient)

Breast cancer gene21+    Her2 FISH

Tissue   

Breast Cancer Prognosis+ Risk of   Recurrence+ Targeted Therapy and Chemotherapy Package (Apply to High-Risk   Patients)

Breast cancer gene21+

( Breast cancer gene9+21)

Tissue   

Breast Cancer Prognosis+ Risk of   Recurrence Package (Apply to Low-Risk Patients)

Breast cancer gene21+

3 times of PEM-CTC

Tissue andperipheral blood sent to   inspect at the same time

The Full Detection Package on Breast   Cancer (Apply to High-Risk Patients)

Breast cancer gene21+     (Breast cancergene9+21) + three times of   PEM-CTC

Tissue andperipheral blood sent to   inspect at the same time

Lung Cancer

Targeted Drug for Lung Cancer+ Basic   Monitoring Package

Lung cancergene10+

3 times of PEM-CTC

Tissue/Peripheral blood 

Lung Cancer EGFR TKI+ Monitoring Package

EGFR ARMS method+

3 times of PEM-CTC

Tissue/Peripheral blood 

Colorectal Cancer

Small Package on Colorectum Detection

KRAS+NRAS+BRAF mutation

Tissue

Peripheral blood

Gastrointestinal Stromal Tumor

Small Package on GIST Detection

C-KIT、PDGFRA mutation

Tissue/Peripheral blood

Glioma

Detection Package on Different Types of Gliomas

IDH1/2 gene mutation, 1p/19q joint loss   of heterozygosity, MGMT methylation(MSP) , TERT promoter mutation

Tissue

General Types of Cancers

Monitoring package of the whole process   on CTC (3 times) 

3 times PEM-CTC

Peripheral blood

 

Note: The package price shall be paid in full.

 

◇ NGS Project List on Accurate medication of Tumor ◇

 

Test Items

Specimen Requirements 

Effective Sequencing Depth

 Clinical Significance

Turn Around Time

*Lung Cancer 5 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide targeted drug use for lung   cancer                

10 Working Days                

Peripheral blood                

5000X                

Lung Cancer 10 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

5000X                

To guide targeted drug use for lung   cancer                

Peripheral blood                

10000X                

*Lung Cancer 13 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide targeted drug use for lung   cancer                

Peripheral blood                

5000X                

Lung Cancer 18+21 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for tumor                

Peripheral blood                

5000X                

To guide the making of individualized therapeutic plan for tumor                

Colorectal Cancer 13+21Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for colorectal cancer                

Gastric Cancer 6+21 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for gastric cancer                

Breast Cancer 9+21 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for breast cancer                

Breast Cancer 9+21 Genes                

Peripheral blood                

5000X                

To guide the making of individualized therapeutic plan for breast cancer                

Ovarian Cancer 6+21 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for ovarian cancer                

Peripheral blood                

5000X                

To guide the making of individualized therapeutic plan for ovarian cancer                

Thyroid Cancer 5+21 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for thyroid cancer                

Melanoma 8+21 Genes                

Paraffin-embedded   tissue/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for melanoma                

Tumor 50 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for tumor                

Tumor 73 Genes                

Paraffin-embedded   tissue    

/Fresh tissue                

2000X                

To guide the making of individualized therapeutic plan for tumor                

Tumor 133 Genes                

Peripheral blood                

10000X                

To guide the making of individualized therapeutic plan for tumor                

Tumor 534 Genes                

(Including TMB and MSI)                

Paraffin-embedded   tissue    

/Fresh tissue                

1000X                

To guide the making of individualized therapeutic plan for tumor                

Peripheral blood                

5000X                

To guide the making of individualized therapeutic plan for tumor                

 

Note: Requirements on specimens of lung cancer gene5 and lung cancer gene13

Peripheral blood: ≥16ml, blood collection with special package boxes, normal temperature preservation and sent for testing within 96 hours

Paraffin section: ≥10 pieces, unstained tissue sections of 5μm thick, the embedding time≤ six months

Tissue for puncture: ≥20 pieces, biopsy or cytology tissue sections of 5μm thick, the embedding time≤ six months, without any treatments of preventing slice escaped from glass slide.

 

Specimen Requirement—Accurate Medication of Tumor NGS Project 

 

Specimen

      Type

Specimen Requirements

Notes

ctDNA Blood Specimen                

10ml of venous blood, transportation   under normal temperature of 4-30℃and delivered for testing within 72 hours                

Special streck blood collection tube                

Tissue for Operation                

Tumor cells proportion> 30%, specimen   size>50mg                

 (as big as a mung bean) 

Special tube for preservation (with   tissue preservation solution), fresh tissue shall be stored in the tube   within half an hour after removal and transported to laboratory within 72   hours under normal temperature                

Tissue for Puncture                

Tumor cells proportion> 30%, 3 pieces                

Paraffin Section                

5-10um of thick; unstained;                 

operative specimen: 5 pieces;                 

specimen for puncture:15 pieces                

Storage time less than 6 months, tumor   cells proportion> 30%; for patients who receive targeted therapy and are drug   resistant, previously stored paraffin specimens are not recommended and could   use the plasma instead                

Pleuroperitoneal Fluid Specimen                

50-100ml, seal the collection bags, and   transport them with ice bags; if conditions permit, cellular sediment is put   into tissue preservation tube after centrifugalization and stored and   transported under normal temperature                

Require that tumor cells shall be   detected in exfoliated cells          

Tumor Disease Tests